In an industry where every molecule, partnership, and project feels like a competition, commercial leaders are being forced to rethink how they build and lead teams. The CDMO and CRO space has shifted; margins are tight, client expectations are rising, and the demand for agility is rewriting what “great” looks like in commercial hiring.
At Vector Talent, we’ve spent years observing how small and mid-sized players punch above their weight. The difference isn’t just in capital or capability, it’s in how they hire, lead, and inspire people. This issue of Vector Talent Insights explores what separates the teams that thrive from those that stall, and how recent moves across the industry reinforce one clear message: the real differentiator in 2026 isn’t technology or capacity...it’s talent.

Two years of turbulence have forced CDMOs to evolve fast. Some organisations are coming out stronger, sharper, and more connected to client needs. Others are still stuck trying to hire as they did five years ago by checking boxes instead of uncovering potential.
The best teams now hire for commercial edge, not just experience. They look beyond CVs to spot behaviours: composure under pressure, ownership, and foresight. It’s not about whether someone has worked for a “big name”; it’s whether they can simplify complex science, connect authentically, and anticipate what the client needs before the client does.
This behavioural lens drawn from The Commercial Recruitment Handbook by Jack Shute transforms recruitment from a transactional process into a strategic act. It’s the mindset behind the phrase:
You’re not just hiring people. You’re building an RFP machine.
Most interviews confirm what’s already on paper. Few reveal how a person thinks.
Winning organisations are changing that. They’re reengineering interviews to dig into judgment, resilience, and motivation. Qualities that turn account managers into commercial athletes.
For example:
Each question pushes candidates beyond rehearsed success stories and into real-world thinking. Because in a tight market, instinct and attitude often outplay scale.
Hiring in a CDMO isn’t a solo act. Every function, from science to operations, shapes the candidate’s experience. The smartest leaders treat hiring like client engagement: they build excitement, maintain momentum, and make every touchpoint consistent.
Before interviews even begin, aligned teams hold pre-briefs, set clear expectations, and define what a “commercial mindset” sounds like. Afterwards, they debrief quickly and consistently. Comparing evidence, not gut feeling.
This discipline turns recruitment from a disjointed exercise into a unified brand moment. Because top candidates, like top clients, can tell when an organisation is aligned.
In today’s market, people don’t just join companies, they join leaders. A strong leader brand has become one of the most powerful assets a CDMO can possess.
It’s what turns credibility into magnetism. When potential hires hear about a manager who develops people, celebrates wins, and shows up authentically, word spreads. The best candidates begin to seek them out.
Leaders who build strong brands:
Each of these habits compounds. Over time, your people become ambassadors for your leadership. Their growth stories become your brand equity.
And in an environment where talent has options, that kind of pull power is invaluable.
CDMO success used to rely on star performers, the “rainmakers.” Now, it’s about balance. Teams win when complementary strengths combine: technical fluency, relationship intelligence, and commercial agility.
The “perfect hire” is disappearing. Leaders are instead designing balanced teams that together cover today’s demands and tomorrow’s opportunities from digital tools to global fluency.
The shift toward partnership-based selling also demands a new kind of commercial professional: one who understands project economics, client strategy, and the operational realities of the site. Technical credibility is no longer optional. Business development leaders must speak the language of science with enough authority to earn trust in the first meeting.
Meanwhile, data literacy and AI openness are fast becoming baseline skills. The future commercial leader doesn’t just use CRM systems, they read insights, forecast trends, and align strategy with analytics.
The winning formula? Build coverage, not perfection.

The headlines across late 2025 tell a consistent story: the CDMO and CRO sectors are in a rebuild and refocus phase and talent sits at the heart of it.
When Argonaut Manufacturing Services Inc. appointed industry veteran Rick Hancock as CEO, it wasn’t just a leadership change. It was a statement about scaling with precision. The company’s expanded Carlsbad campus and new fill-finish capacity are about growth, yes. But also about the kind of leadership that can integrate new capabilities while keeping culture intact. Appointing a proven leader signals to both investors and employees that stability and vision are being prioritised.
Similarly, Skyepharma- Fully integrated CDMO’s appointment of Sébastien Mas as CEO after its acquisition by Oleron Pharma underscored a growing trend: combining strategic mergers with leadership continuity. In recruitment terms, it reinforces how critical internal succession planning and cultural alignment have become. When acquisition dust settles, the leaders who keep teams engaged determine whether synergies are realised or lost.
The same theme plays out across Biomerica, Inc.’s expansion into broader CDMO services, LTS Lohmann Therapy Systems, Corp.’s acquisition of Renaissance Lakewood, LLC, and BIOVECTRA’s partnership with Revolution Biomanufacturing Inc.. Each reflects a market shifting from pure capacity growth to capability orchestration. Where collaboration and technical fluency outweigh headcount alone.
These moves have clear implications for talent:
Even in the CRO space, the narrative aligns. Worldwide Clinical Trials recently appointed John Capicchioni as SVP for Early Phase, highlighting the growing intersection of science, data, and business development. His mandate, integrating commercial strategy with operational execution, mirrors a broader truth: future commercial leaders will be connectors, not silos.
In short, the CDMO and CRO sectors are undergoing a leadership evolution. One where recruitment strategy equals business strategy. Every appointment, expansion, or partnership carries a ripple effect across talent attraction, brand reputation, and organisational identity.
So, what does all this mean for commercial leaders right now?
It means the fundamentals still matter but how you deliver them has changed. Clients still value trust. Teams still thrive on purpose. But in 2026, trust is built through transparency, and purpose is sustained through adaptability.
For those leading hiring efforts:
The market may be competitive, but opportunity remains abundant for those who can align people, process, and purpose. Because in the end, growth in this industry has always depended on the same formula: great science, great partnerships, and great people.
This newsletter shares only part of the story. For a deeper dive including interview frameworks, behavioural assessment models, and leadership brand strategies, reach out to Jack Shute for a copy of the Commercial CDMO Recruitment Handbook.